NPTE Lab Values Practice Questions

10 Free NPTE Lab Values Practice Questions (2026)

10 NPTE-style lab values practice questions covering the values that change physical therapy decisions — hemoglobin, platelets, glucose, potassium, oxygen saturation, neutrophil counts, sodium, troponin, HbA1c, and albumin. Multiple-choice format with full rationales. Written and reviewed by a licensed Doctor of Physical Therapy.

The chart review the NPTE expects you to do

Lab values appear on the NPTE the same way they appear in acute care: a number in the chart that determines whether today’s session happens, gets modified, or gets escalated to the medical team. The exam tests three levels — knowing the normal range, recognizing when a value is critically abnormal, and knowing the physical therapy action attached to it. The values below are the ones that most reliably carry a testable PT decision.

0 of 10 answered
Hemoglobin
Question 1 of 10
A physical therapist reviews the morning labs of a 68-year-old male on the medical floor, scheduled for a progressive ambulation session. Hemoglobin is 7.4 g/dL (reference 13.5–17.5 g/dL for males). The patient reports fatigue but wants to participate. Which of the following is the MOST appropriate action?
Platelets
Question 2 of 10
A 54-year-old female undergoing chemotherapy has a platelet count of 15,000/mm³ on morning labs (reference 150,000–400,000/mm³). Her planned session includes progressive resistance exercise. Which of the following is the MOST appropriate action?
Blood Glucose
Question 3 of 10
A 41-year-old male with type 1 diabetes checks his blood glucose before a scheduled outpatient exercise session. The reading is 58 mg/dL. He reports feeling “a little shaky.” Which of the following is the MOST appropriate action?
Potassium
Question 4 of 10
A physical therapist reviews the chart of a 77-year-old female on a loop diuretic before a scheduled session. This morning’s potassium is 2.9 mEq/L (reference 3.5–5.0 mEq/L). Which of the following is the MOST appropriate action?
Oxygen Saturation
Question 5 of 10
A 72-year-old male with COPD is ambulating in the hallway with a physical therapist. His resting SpO2 was 93% on room air. During ambulation he becomes short of breath, and pulse oximetry reads 85%. Which of the following is the MOST appropriate IMMEDIATE action?
White Blood Cells — Neutropenia
Question 6 of 10
A 47-year-old female receiving chemotherapy has an absolute neutrophil count (ANC) of 400/mm³. She is on neutropenic precautions. Which of the following BEST describes the appropriate physical therapy approach?
Sodium
Question 7 of 10
A physical therapist arrives to treat an 81-year-old male admitted two days ago. Morning labs show a sodium of 118 mEq/L (reference 135–145 mEq/L). The nurse mentions he has been increasingly confused since last evening. Which of the following is the MOST appropriate action?
Cardiac Markers — Troponin
Question 8 of 10
A 63-year-old male admitted overnight with chest pain is on the therapist’s morning list for evaluation. Chart review shows his troponin drawn four hours ago is elevated and trending upward, with a repeat draw pending. Which of the following is the MOST appropriate action?
Hemoglobin A1c
Question 9 of 10
A 52-year-old female with type 2 diabetes tells her physical therapist that her recent HbA1c was 9.2%, though her fasting glucose “was fine this morning.” Which of the following BEST describes what the HbA1c value indicates?
Albumin & Wound Healing
Question 10 of 10
A physical therapist is treating a 79-year-old male with a stage 3 sacral pressure injury that has shown minimal healing over three weeks despite appropriate wound care and offloading. Chart review shows a serum albumin of 2.4 g/dL (reference 3.5–5.0 g/dL). Which of the following BEST explains the relevance of this value?
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Every lab value question is really a “treat, modify, or escalate” question
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About This Topic

How Lab Values Are Tested on the NPTE

Lab values on the NPTE live inside the acute-care and safety threads of the FSBPT content outline — scored across the cardiopulmonary, metabolic, and safety domains rather than as a section of their own. Try our free 20-question timed NPTE practice test, Pharmacology practice questions, or Other Systems practice questions to see how chart-review details are framed across the exam.

The values that carry a testable PT action
Hemoglobin — severe anemia limits activity to essential mobility
Platelets — severe thrombocytopenia holds exercise; moderate levels drop resistance
Glucose — below 70 treat before exercising; markedly high values defer
Potassium & sodium — electrolyte extremes are hold-and-notify values
SpO2 — desaturation during activity stops the activity
ANC — severe neutropenia flips the direction of precautions
INR — over-anticoagulation defers high-force techniques
Troponin — rising values mean no exertion until cleared
HbA1c — long-term glycemic control shapes the plan, not today’s session
Albumin — protein depletion explains stalled wound healing

Note that facility protocols vary on exact activity thresholds, and the NPTE writes around that variation: questions test the CATEGORY of response — proceed, modify, or hold-and-communicate — anchored to clearly abnormal values, not borderline cases where guidelines disagree. If a vignette gives you a value far outside its reference range plus a matching symptom, the exam is asking whether you recognize the emergency. See our full NPTE exam format breakdown for how these items fit into the 225-question structure.

The pattern to recognize

Lab value vignettes almost always pair the number with its symptom — hypokalemia with palpitations, hyponatremia with confusion, anemia with fatigue, hypoglycemia with shakiness. The pairing is the test: it asks whether you connect what the patient is showing to what the chart already explains. And the wrong answers follow a pattern of their own — they treat the symptom as a therapy obstacle to work around (cue more, slow down, adapt the session) instead of the medical finding it is. When a symptom and an abnormal value point at each other, the answer is nearly always communicate, not accommodate.

Cross-Content Reasoning

Where Lab Values Connect Across the Exam

Lab values are the acute-care face of content tested elsewhere on the exam. The pharmacology thread supplies the causes: the loop diuretic behind the hypokalemia, the warfarin behind the INR, the insulin timing behind the hypoglycemia — a medication in the history usually explains the abnormal value in the chart. The cardiopulmonary section supplies the monitoring context: SpO2 thresholds, troponin and cardiac stability, hemoglobin and aerobic capacity all live at that border.

The other systems connect through metabolism and healing — glucose and HbA1c to diabetes management, albumin to the integumentary section’s wound questions — while the non-systems section supplies the safety framework: infection control for the neutropenic patient, emergency response for the hypoglycemic one, and the professional judgment of when a finding requires physician communication before treatment.

That last connection is the deepest one. Lab value questions are screening questions wearing numbers: the same recognize-and-refer judgment tested with visceral referral patterns and red flags, except here the red flag arrives pre-measured. A student who has internalized the screening mindset — mechanical problems get treated, medical problems get escalated — will answer most lab questions correctly even when a specific threshold is fuzzy.

Study tip

Build a three-column lab card: value, reference range, and the ONE action an abnormal result triggers. Ten rows cover the values above. Then add a fourth column linking each value to its usual cause — the diuretic, the chemotherapy, the anticoagulant — because the exam loves to test the value and its cause in the same vignette. Review it alongside your pharmacology card; they are two halves of the same chart review, and our complete NPTE study guide covers how to fold both into a full study plan.

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