NPTE Non-Systems Practice Questions

10 Free NPTE Non-Systems Practice Questions (2026)

10 NPTE-style non-systems practice questions covering equipment and devices, therapeutic modalities, safety and protection, professional responsibilities, and research and evidence-based practice — 36 to 45 items per the official FSBPT blueprint. Multiple-choice format with full rationales. Written and reviewed by a licensed Doctor of Physical Therapy.

The content area nobody studies

Non-systems accounts for 36 to 45 scored items on the NPTE per the FSBPT blueprint — more than cardiopulmonary. Yet it is the content area students spend the least time preparing, because it does not map to a body system or a clinical rotation. Modality parameters, wheelchair measurements, infection control, research statistics, and professional ethics are all highly testable, highly specific, and easy points to lose. Students who deliberately prepare non-systems gain ground on everyone who ignores it.

0 of 10 answered
Therapeutic Modalities — Safety
Question 1 of 10
A 72-year-old male with chronic cervical pain requests transcutaneous electrical nerve stimulation (TENS), which he states helped him in a previous episode of care. His medical history includes hypertension and a demand-type cardiac pacemaker implanted 2 years ago. Which of the following is the MOST appropriate course of action?
Equipment & Devices — Wheelchair Prescription
Question 2 of 10
A physical therapist is measuring a patient for a standard manual wheelchair. The measurement across the widest portion of the patient’s hips in sitting is 16 inches. Which of the following is the MOST appropriate seat width for this patient’s wheelchair?
Safety & Protection — Infection Control
Question 3 of 10
A physical therapist is scheduled to treat a hospitalized patient with confirmed Clostridioides difficile (C. diff) infection. Which of the following infection control measures is MOST important for the therapist to implement after completing the treatment session?
Research & EBP — Diagnostic Accuracy
Question 4 of 10
A physical therapist is reviewing the diagnostic accuracy of a clinical special test that has a reported sensitivity of 0.97 and a specificity of 0.55. Based on these values, this test is MOST useful for which of the following purposes?
Professional Responsibilities — Patient Autonomy
Question 5 of 10
A 58-year-old female recovering from a total knee arthroplasty declines to participate in her scheduled physical therapy session, stating she is exhausted and in too much pain today. The therapist explains the risks of missing early post-operative mobility, including stiffness and delayed recovery, but the patient still declines. Which of the following is the MOST appropriate action?
Therapeutic Modalities — Ultrasound Parameters
Question 6 of 10
A physical therapist plans to use therapeutic ultrasound to heat the piriformis muscle in a patient with deep buttock pain. Which of the following parameter selections is MOST appropriate to reach the target tissue depth?
Equipment & Devices — Assistive Device Fitting
Question 7 of 10
A physical therapist is fitting axillary crutches for a patient who is non-weight-bearing on the left lower extremity following an ankle fracture. With the patient standing and the crutch tips positioned approximately 6 inches lateral and 6 inches anterior to the feet, which of the following BEST describes correct crutch fit?
Safety & Protection — Medical Emergency
Question 8 of 10
A 49-year-old male with type 1 diabetes is 20 minutes into an outpatient exercise session when he becomes pale, diaphoretic, and tremulous, and begins responding slowly to questions. Which of the following is the MOST appropriate immediate action?
Research & EBP — Study Design
Question 9 of 10
A physical therapist wants to determine whether a new manual therapy protocol causes greater improvement in shoulder range of motion than standard care. Which of the following study designs provides the STRONGEST evidence of a cause-and-effect relationship between the intervention and the outcome?
Professional Responsibilities — Mandatory Reporting
Question 10 of 10
During a home health visit, a physical therapist notes multiple bruises in various stages of healing on the forearms and trunk of an 84-year-old female patient. When asked, the patient becomes withdrawn and states her adult son, who is her caregiver, “gets frustrated sometimes.” Which of the following is the MOST appropriate action for the therapist to take?
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Non-systems is 36–45 items on the NPTE — more than cardiopulmonary
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About This Content Area

NPTE Non-Systems Content Breakdown

Non-systems is the content on the NPTE-PT that does not belong to any single body system — 36 to 45 scored items per the official FSBPT blueprint, which makes it larger than cardiopulmonary and second only to musculoskeletal and neuromuscular. It is also the content students most consistently skip during preparation, because it never had its own clinical rotation and it feels like miscellaneous material. On exam day, that neglect shows. Try our free 20-question timed NPTE practice test, Musculoskeletal practice questions, or Neuromuscular practice questions to see where your preparation actually stands.

What the non-systems section covers
Equipment, devices, and technologies — wheelchairs, assistive devices, orthotic and prosthetic fit
Therapeutic modalities — parameters, indications, contraindications
Safety and protection — infection control, emergency response, fall prevention
Professional responsibilities — ethics, consent, documentation, mandatory reporting
Research and evidence-based practice — study design, statistics, diagnostic accuracy
Standard precautions and sterile technique
Roles, supervision, and delegation within the PT/PTA team
Legal and regulatory obligations in patient care

Non-systems questions differ from body-system questions in an important way: many of them have precisely correct answers. A wheelchair seat width is the hip measurement plus 2 inches. C. diff requires soap and water. 1 MHz ultrasound reaches deep tissue. A sensitive test rules out. These are not judgment calls — they are learnable facts, which makes non-systems the highest return-on-study-time content area on the exam. See our full NPTE exam format breakdown for how these items fit into the 225-question structure.

The pattern to recognize

Non-systems questions love the almost-right answer that would be correct in the more common situation. Alcohol sanitizer is correct hand hygiene — except for C. diff. TENS is a reasonable pain modality — except with a demand pacemaker. Continuing a session at lower intensity is reasonable — except when the symptoms are a medical emergency. When a non-systems question includes a specific detail in the vignette (the pacemaker, the diagnosis, the diabetes), that detail is almost always the reason the standard answer is wrong. Read every rationale above and note which vignette detail changed the answer.

Cross-Content Reasoning

How Non-Systems Shows Up Inside Every Other Content Area

Non-systems knowledge is unusual because it is tested twice: once in dedicated non-systems items, and again woven into body-system questions. A musculoskeletal question about post-surgical rehabilitation may hinge on the weight-bearing restriction and the correct assistive device. A cardiopulmonary question may turn on recognizing when vital signs require stopping the session — a safety decision, not a cardiopulmonary one. A neuromuscular question about a patient with a stroke may actually be testing wheelchair prescription or caregiver education.

The same is true in reverse: dedicated non-systems items borrow clinical context from every system. The modality question includes a cardiac history. The infection-control question specifies the pathogen. The ethics question involves a post-surgical patient. You cannot fully separate non-systems preparation from the rest of the exam — which is exactly why students who skip it lose points everywhere, not just in one section.

The professional responsibilities and research domains also carry the questions students find hardest to guess: mandated reporting thresholds, supervision and delegation rules for the PT/PTA team, informed consent and refusal, sensitivity versus specificity, and levels of evidence. These reward direct study in a way clinical intuition cannot replace. PTA candidates face a parallel non-systems section on the NPTE-PTA with additional emphasis on the scope of the PTA role.

Study tip

Build a one-page reference sheet for the pure-recall non-systems facts: modality parameters and contraindications, wheelchair and assistive device measurements, isolation precautions by pathogen, and the SnNout/SpPin rules. Review it daily during your final two weeks — these are the only NPTE points you can secure through memorization alone, and our complete NPTE study guide covers how to fit this into a full study plan.

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10 questions give you a snapshot. Practitionr’s AI gives you a full diagnostic across every non-systems domain — modalities, equipment, safety, research, professional responsibilities — then rebuilds your study plan around exactly where you need more work. No credit card required.

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