NPTE-PTA Musculoskeletal Practice Questions

10 Free NPTE-PTA Musculoskeletal Practice Questions (2026)

10 NPTE-PTA-style musculoskeletal practice questions covering the largest content area on the physical therapist assistant exam, 31 to 40 scored items per the official FSBPT blueprint. Post-surgical precautions, goniometry and manual muscle testing, fracture and weight-bearing rules, directional preference, and when to hold treatment and call the PT. Multiple-choice format with full rationales. Written and reviewed by a licensed Doctor of Physical Therapy.

How the NPTE-PTA tests musculoskeletal content

PTA musculoskeletal questions rarely ask you to diagnose. They hand you a plan of care written by the supervising PT and ask whether you can carry it out safely: collect the right data, apply the right precaution, progress the right exercise, and recognize the finding that means stop and call. Most wrong answers are either a PT-level decision (changing the plan, performing a thrust manipulation) or a safe-looking intervention that violates a healing timeline. Read every vignette for the precaution and the post-op week before you read the options.

0 of 10 answered
Post-Surgical Precautions
Question 1 of 10
A physical therapist assistant is treating a 71-year-old woman two days after a right total hip arthroplasty performed through a posterolateral approach. The supervising PT’s plan of care lists standard posterior hip precautions. During the session the patient reaches down from the edge of the bed to pull on her right sock. Which of the following is the MOST appropriate action?
Tissue Healing Timelines
Question 2 of 10
A physical therapist assistant is treating a 48-year-old man three weeks after arthroscopic rotator cuff repair of the supraspinatus. The supervising PT’s plan of care specifies passive range of motion only, with no active elevation until week six. The patient reports that his shoulder feels strong and asks to begin lifting the arm on his own. Which of the following is the MOST appropriate response?
Data Collection: Goniometry
Question 3 of 10
A physical therapist assistant is measuring knee flexion range of motion in supine for a patient six weeks after a tibial plateau fracture, as directed in the supervising PT’s plan of care. Which of the following goniometer alignments is correct?
Data Collection: Manual Muscle Testing
Question 4 of 10
During a reassessment of quadriceps strength directed by the supervising PT, a physical therapist assistant positions the patient sitting with the knee flexed over the edge of the table. The patient extends the knee through the full available range against gravity but cannot hold the position when the PTA applies any manual resistance. Which of the following manual muscle test grades is MOST appropriate?
Red Flags: Ankle Injury
Question 5 of 10
A physical therapist assistant is treating a 24-year-old woman referred two days after an inversion ankle sprain. The supervising PT’s plan of care calls for protection, compression, elevation, and weight bearing as tolerated. Today the patient reports she has been unable to take four steps on the limb since the injury, and the PTA finds bone tenderness along the posterior edge of the distal six centimeters of the lateral malleolus. Which of the following is the MOST appropriate action?
Exercise Progression: ACL Reconstruction
Question 6 of 10
A physical therapist assistant is treating a 19-year-old athlete two weeks after anterior cruciate ligament reconstruction with a bone-patellar tendon-bone autograft. The supervising PT’s plan of care includes quadriceps strengthening in the early protective phase. The patient asks to use the seated knee extension machine with resistance through the last 30 degrees of extension. Which of the following is the MOST appropriate intervention for quadriceps strengthening at this stage?
Conditions: Rheumatoid Arthritis
Question 7 of 10
A physical therapist assistant is treating a 56-year-old woman with rheumatoid arthritis whose plan of care includes progressive resistive exercise for grip and wrist strength. She arrives today reporting that she woke with morning stiffness lasting over two hours, and the PTA observes that the metacarpophalangeal joints of both hands are warm, swollen, and painful to touch. Which of the following is the MOST appropriate modification?
Weight-Bearing Status
Question 8 of 10
A physical therapist assistant is performing gait training with a 79-year-old man four days after open reduction and internal fixation of a left intertrochanteric hip fracture. The surgeon’s order and the supervising PT’s plan of care specify toe-touch weight bearing on the left lower extremity. During ambulation with a front-wheeled walker, the PTA observes the patient loading the left leg with what appears to be about half of his body weight. Which of the following instructions is MOST appropriate?
Directional Preference: Low Back
Question 9 of 10
A physical therapist assistant is treating a 38-year-old man with low back pain and intermittent right leg symptoms. The supervising PT’s evaluation found a directional preference for extension, and the plan of care includes repeated prone press-ups. During today’s session, after a set of ten press-ups, the patient reports that his back feels better but the pain has moved from his buttock down to his calf for the first time. Which of the following is the MOST appropriate action?
Post-Surgical Precautions: Spine
Question 10 of 10
A physical therapist assistant is seeing a 62-year-old woman on postoperative day two after a two-level posterior lumbar fusion. The supervising PT’s plan of care includes bed mobility and transfer training with spinal precautions. To get out of bed, the patient begins to sit straight up by flexing the trunk and pulling with the arms on the bed rail. Which of the following is the MOST appropriate instruction?
0/10
Musculoskeletal is 31 to 40 of the 140 scored NPTE-PTA items, the largest single content area
Get Your Personalized NPTE-PTA Study Plan → Try the 10 General NPTE-PTA Questions

About This Content Area

NPTE-PTA Musculoskeletal Content Breakdown

The musculoskeletal system is the largest content area on the NPTE-PTA, 31 to 40 of the 140 scored items per the official FSBPT NPTE-PTA content outline, effective January 2024. The Federation of State Boards of Physical Therapy splits those items into three categories: physical therapy data collection (9 to 12 items), diseases and conditions that impact effective treatment (10 to 13), and interventions (12 to 15). Try our free 20-question NPTE-PTA practice test, Neuromuscular practice questions, or the 10 general NPTE-PTA practice questions to see how this content sits alongside the rest of the exam.

What the PTA musculoskeletal section covers
→Data collection: goniometry landmarks, manual muscle test grades, posture and movement analysis, gait observation, outcome measures
→Joint biomechanics and anatomy of the musculoskeletal system: synovial joints and their arthrokinematics, synarthroses such as the sutures and the pubic symphysis, the glenohumeral joint and scapular rhythm, hip internal rotation and the capsular pattern, ankle dorsiflexion and foot pronation during gait
→Diseases and conditions: fractures, arthroplasty, ligament and tendon repair, osteoarthritis, rheumatoid arthritis, connective tissue disorders
→Medical management that changes the plan: imaging, surgical procedures, weight-bearing orders, pharmacology
→Interventions: range of motion, stretching, strengthening progression, mobilization grades within the plan of care, gait and functional training
→Adverse effects and complications of interventions, including those from treatment of other systems

What makes the PTA version different from the PT exam is the question frame. The NPTE-PT musculoskeletal questions ask you to examine, diagnose, and decide, which is why the PT exam leans on the orthopedic special test: the Lachman test and anterior drawer test for the anterior cruciate ligament, the posterior drawer test for the PCL, and the impingement and labral tests of the shoulder. The PTA exam does not ask you to select or perform a special test to make a diagnosis. It expects you to recognize what a documented special test result means for the plan of care (a positive Lachman test in the chart tells you why the knee is braced and why open-chain extension is restricted) and to carry out the interventions the PT chose. See our full NPTE-PTA exam format breakdown for how these items fit into the 180-question structure.

Conditions the PTA musculoskeletal section returns to most
→Shoulder: adhesive capsulitis (the frozen shoulder, with its capsular pattern of lost external rotation), rotator cuff repair, glenohumeral joint instability, pectoralis major and biceps tendon injury
→Elbow, wrist, and hand: lateral epicondylalgia, carpal tunnel syndrome, thoracic outlet syndrome and its postural contributors, rheumatoid arthritis of the hand
→Hip and knee: arthroplasty precautions, hip fracture and weight bearing, osteoarthritis, ACL and meniscal repair, patellofemoral pain
→Foot and ankle: Achilles tendon rupture and tendinopathy, plantar fasciitis, lateral ankle sprain, ankle dorsiflexion loss and compensatory pronation
→Spine: lumbar fusion precautions, directional preference, spinal stenosis, cervical radiculopathy, osteoporosis and compression fracture
→Pediatric and systemic: scoliosis, juvenile idiopathic arthritis, Osgood-Schlatter disease, osteogenesis imperfecta
The pattern to recognize

Almost every PTA vignette in the musculoskeletal system contains a boundary: a post-op week, a precaution, a weight-bearing order, a mobilization grade, or a plan of care that says what the PTA may do. The wrong answers cross that boundary, either by doing more than the plan allows (a thrust, a new exercise, an advanced weight-bearing status) or by ignoring a finding that should stop the session (peripheralization, Ottawa criteria, an inflamed joint). Find the boundary first, then pick the answer that stays inside it or escalates to the PT.

Cross-Content Reasoning

Where Musculoskeletal Content Connects Across the NPTE-PTA

Musculoskeletal items borrow from every other section. The weight-bearing and precaution rules on this page are the same ones the non-systems section tests through assistive device selection and gait patterns, and the Ottawa rules and red-flag reasoning here reappear as safety and professional responsibility items. The ACL and rotator cuff timelines connect to therapeutic modalities, where the same healing phases decide whether cryotherapy, electrical stimulation, or ultrasound is appropriate.

The neuromuscular section shares the orthopedic surgery population: a patient with Parkinson’s disease after a hip fracture, or a stroke survivor with a glenohumeral joint subluxation, is written as a system-interaction item that counts toward the other systems total, alongside the integumentary, lymphatic, endocrine, and genitourinary items. Rheumatoid arthritis sits at the same intersection, an autoimmune condition with musculoskeletal, cardiopulmonary, and medication effects that the exam can file under more than one system, and so does lymphatic involvement after breast cancer surgery, where lymphedema precautions change how the shoulder is loaded. Integumentary items overlap the same way: an Achilles tendon repair carries an incision and a cast, and the skin check is part of the musculoskeletal session.

And the cardiopulmonary section supplies the monitoring layer: vital-sign responses during gait training after hip fracture, sternal precautions after cardiac surgery, and the exercise tolerance of a deconditioned patient all decide how far a musculoskeletal intervention can be pushed in a single session.

Study tip

Build a one-page precaution sheet: posterior and anterior hip approaches, lumbar fusion, rotator cuff repair, Achilles tendon repair, ACL reconstruction with each graft type, and sternal precautions, each with the motions to avoid and the week the restriction lifts. Pair it with the weight-bearing ladder (NWB, TTWB, PWB, WBAT, FWB), the goniometry landmark triads for the shoulder, elbow, hip, knee, and ankle, and the capsular patterns (adhesive capsulitis loses external rotation first, the hip loses internal rotation first). Those sheets cover most of the recall the musculoskeletal system demands, and our complete NPTE-PTA study guide shows how to fold them into a full study plan.

Want to Know Which Musculoskeletal Rules You Would Miss?

10 questions give you a snapshot. Practitionr’s AI tracks your musculoskeletal accuracy topic by topic, precautions, data collection, and progression included, then rebuilds your NPTE-PTA study plan around exactly where you need more work. No credit card required.

Free NPTE-PTA Study Resources